The CEL is a "flag" indication that there is something "not right" with the engine, thus the term Engine Check Light... If the motor misses for 3 firings, it throws a code to the ecu to indicate a POSSIBLE problem and the problem can be analysed with looking up the code. The code usually stays there untill cleared, or 13 or so restarts with no recurrence, then it would clear by itself. If it is a misfire, it could simply have been a moisture droplet that was in the fuel system, and not a serious problem at all. If after clearing the code and it IMMEDIATELY re-appears, then, I might be a little more concerned. otherwise, I would not. If it came on when I was 20 miles into a 500 mile trip, I would keep an ear to the motor's smootheness, but would not scuttle the trip unless the engine runs really bad. I have found someimes, while the motor is missing, turning off (reboot the ECU) the engine for a few seconds and restarting corrects the miss, but the ECL has to be reset with a tool. I installed a scanguage in my car, and it easily can analyze and clear all the CEL notifications.
Ha ha maybe this now will be more to think about for you ....
There are inexpensive OBD-II (OBD2) check tools that might be useful for you ...
Got mine from E-Bay. Check that it's usable on your vehicle before you purchase. I spent $35 on mine, just for peace of mind.
Aloha !